Research in the Clinical Neurophysiology group
CNPH is at the interface of neuroscience, neurophysiology and clinical neurology, focusing on cerebral ischemia and epilepsy. In addition to improve understanding of pathophysiology, we aim to develop novel diagnostic tools and treatments. Our research is truly translational: from the UT to the clinic and back.
The EEG is a key clinical and research tool. EEG signal analysis includes various machine learning techniques to improve diagnostic values and (bedside) application. Applied EEG studies are complemented by biophysical modeling and simulation for improved understanding of underlying neuronal dynamics and prediction of treatment effects. In addition, we use in vitro models consisting of cultured neurons (from rodent or human induced pluripotent stem cells) on multi-electrode arrays to study basic neuronal and synaptic functioning, identify treatment targets, and screen treatments.