The research group led by Dr. Joke den Haan (Joke den Haan - Immunology Amsterdam
) is international and generates different types of cancer nanovaccines (liposomes, nanobodies, antibodies) that are targeted to macrophages or dendritic cells. We use both human antigen presenting cells and T cells as well as in vivo
animal models to test our vaccination approaches and employ (unbiased) multiparameter spectral cytometry, ELISA, and microscopy read-outs. The research technician will be involved in the generation and analyses of the immunostimulatory effects of nanobody and liposomal vaccines to induce T cells that can inhibit cancer outgrowth.About your role
A position is vacant for a research technician in the group of dr. Joke den Haan with the focus on the development of novel types of cancer vaccines. In this position you will collaborate with postdocs and PhD students for production of vaccines, detection of uptake and presentation of vaccines by antigen presenting cells and for their capacity to activate T and B cells. We use in vitro cell culture systems and in vivo models, multiparameter spectral flow cytometry, and molecular biology and biochemistry techniques to produce and evaluate the vaccines for their immunostimulatory effects.