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PhD-student - Advanced engineering of human pumping heart tissues

PhD-student - Advanced engineering of human pumping heart tissues

Published Deadline Location
25 Apr 31 May Enschede

Job description

The prospective PhD candidate will operate as part of a recently awarded EIC Pathfinder Challenge Consortium ("BioRobot-MiniHeart"). The PhD candidate position is available immediately. In this project we will use beyond-state-of-the-art solutions to engineer a living functional heart tissues with complex architectures, which will be used as in vitro models for fundamental research as well as drug screening.

The aim of the presently available PhD-position is to generate key cardiac cell-types from human iPS cells for the engineering of a functional pumping mini-heart. You will therefore work on the multidisciplinary interface of stem and cardiac cell biology, molecular engineering, materials science and microengineering. This will develop a wide skill set which will include tissue engineering, induced pluripotent cell culture and differentiation, CRISPR-Cas9-mediated genome editing, microfabrication, 3D printing, assay development and writing high impact scientific publications.

Specifications

University of Twente (UT)

Requirements

  • You hold a master's degree in Biomedical Engineering, Materials Science, Biomedical Sciences, or an equivalent master's education;
  • You have excellent analytical skills and an innate ability for solution oriented problem solving;
  • You have experience in stem cell cultures and differentiation, CRISPR-Cas-9 mediated genome editing, cardiovascular biology, and/or tissue engineering.
  • You have a strong interest in 3D (bio) printing, microfluidics, microfabrication, physics and advanced optical imaging techniques will be considered as a benefit.
  • You possess excellent social and communication skills, in academic as well as non-academic contexts.
  • You love working in a team in which fundamental and applied research cross-fertilize.
  • You have a creative and critical attitude, combined with perseverance and being flexible and stress-resistant.
  • You are fluent in English language skills, both in speaking and writing.

Conditions of employment

  • Fully paid fulltime position for four years
  • The university offers a dynamic ecosystem with enthusiastic colleagues in a stimulating scientific environment.
  • The PhD salary is € 2.541,- in the first year and increases to € 3.247,- in the fourth year.
  • A holiday allowance of 8% of the gross annual salary and a year-end bonus of 8.3%.
  • A solid pension scheme.
  • A professional and personal development program within Graduate School Twente.
  • The number of holiday hours for full-time employment is 232 hours per calendar year.
  • A personal development program within the Twente Graduate School.

Department

The PhD-candidates will work in the Passier Lab, which is part of the department of Applied Stem Cell Technologies AST. We use stem cell and molecular technologies, organ-on-chip-devices, advanced tissue engineering to emulate and understand organ development and function in health and disease. We AST is part of the Technical Medical Centre of the University of Twente, which is widely recognized for its cutting-edge developments in biomedical technology and advanced biomanufacturing.

Additional information

For questions about the position, please contact Robert Passier, Professor, at robert.passier@utwente.nl

Practical information and applying
You can apply until 31st of May 2023, exclusively using the button below. Kindly address your application to Robert Passier. Please fill in the application form and attach the following documents:
  • A letter of motivation, emphasizing your specific interest and motivation,
  • Your CV including the contact details of three references.
  • Academic transcript of B.Sc. and M.Sc. education.
An interview and a scientific presentation will be part of the selection procedure.
High Tech and Human Touch

Join the university of technology that puts people first. Create new possibilities for yourself, your colleagues and society as a whole. Using modern technology and science to drive innovation, change and progress. That’s what it means to work at the University of Twente.

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Specifications

  • PhD
  • Health
  • max. 40 hours per week
  • €2541—€3247 per month
  • University graduate
  • 1213

Employer

University of Twente (UT)

Learn more about this employer

Location

Drienerlolaan 5, 7522NB, Enschede

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Application procedure

Application procedure

Make sure to apply no later than 31 May 2023 23:59 (Europe/Amsterdam).