Inherited Metabolic Diseases are severe and chronic diseases, which often affect children. They are individually rare, but altogether we know more than 1,800 different metabolic diseases. The Recon4IMD project
aims to accelerate diagnosis and personalise management of these diseases. As a postdoc you will develop genome-scale, personalised computational models of metabolic networks, based on genomics, transcriptomics, proteomics, and metabolomics datasets of individual patients. You will implement kinetic properties of enzymes, thus exploring the potential of hybrid stoichiometric-kinetic models. In the European Recon4IMD consortium you will collaborate with world-leading experts in computational modeling of metabolic networks, as well as with clinicians, laboratory specialists, and metabolomics experts.