Inflammatory bowel disease (IBD) constitutes a group of incurable, chronic, relapsing diseases of the gastrointestinal tract, stemming from a dysregulated interplay between the environment and the immune system in genetically susceptible individuals. We are seeking a skilled Bioinformatics Data Analyst with a passion for leveraging computational approaches to understand the molecular mechanisms underlying IBD and its phenotypes. In this role, you will collaborate closely with our interdisciplinary team of clinicians, geneticists, and molecular biologists to analyze large-scale omics datasets, including genomics, transcriptomics, proteomics, and microbiome data.

Your primary focus will be providing bioinformatic support for the researchers in their analyses of high-dimensional data. The ideal candidate will be able to:

• Work with in-house generated or publicly available genetic, epigenetic, transcriptomic, proteomic data at bulk and single-cell level;
• Aid in the development pipelines for analyzing high-dimensional biological data;
• Performing data preprocessing, quality control, and normalization on omics datasets for Biomarker identification and molecular pathways analyses;
• Be able to work on multi-omics data integration;
• Be able to master data visualization techniques to communicate findings effectively to both technical and non-technical stakeholders;
• Be willing to stay updated on the latest bioinformatics methodologies and contribute to the development of novel analytical approaches.

• You possess a master's degree in biomedical data sciences or a related life-science field with a strong emphasis on applied data analysis and/or machine learning;
• You have prior experience in analyzing omics data, such as (single-cell/bulk) RNA-sequencing, DNA methylation microarrays, or metagenomics sequencing. Previous exposure to single-cell omics technologies, such as single-cell RNA-sequencing, is desired;
• Proficiency in R, Python, and bash scripting, along with familiarity working in a Linux environment using schedulers, is expected;
• Previous exposure to workflow management systems like Snakemake and/or Nextflow is preferred;
• Good verbal communication skills in English are essential;
• You are inherently driven, scientifically curious, and adept at collaborative teamwork.

• A flying start to your career in scientific research.
• Plenty of room for personal development with a wide range of training & development of academic skills
• Working on large-scale and own research, with motivated colleagues
• A contract for 12 months with the prospect of extension for another 12 months.
• Salary scale: 8M: € 3.401 tot € 4.816 bruto (based on a fulltime workweek), depending on experience.
• Additional benefits including an 8.3% end-of-year bonus and 8% holiday pay. Calculate your net salary here.
• Your pension is accrued at BeFrank. A modern, understandeble en fair pension
• Excellent accessibility with public transportation and reimbursement of a large portion of your travel expenses. Additionally, we have plenty of parking spaces at the AMC location and a good bicycle scheme.

Amsterdam UMC

You will be collaborating with researchers at the Tytgat Institute for Liver and Intestinal Research and the Department of Gastroenterology at the AmsterdamUMC. Both departments are home to dedicated researchers engaged in fundamental, applied, and clinical research within the fields of gastroenterology and hepatology. The candidate will be actively involved in facilitating projects in the context of inflammatory bowel disease. While you will primarily work with colleagues at the Tytgat Institute and Department of Gasteroenterology, we actively encourage you to collaborate with peers outside the Tytgat Institute to facilitate knowledge exchange.