We are looking for a PhD candidate in the Biochemistry department at the Cardiovascular Research Institute Maastricht (CARIM) for a research project funded by the Netherlands Organization for Scientific Research (NWO Vidi 91716421).

The goal of the project is to disclose underlying signaling mechanisms for the role of platelets in recurrent cardiovascular events, such as myocardial infarction and stroke, and to find new reference points for antithrombotic medication. The core of the PhD project is comprised of cell biological work with a clear translational link.

The project involves a local team of platelet biologists, physicians and a drug design specialist with ample input from (inter)nationally-based biomedical engineers and proteomics specialists. Research techniques include advanced microscopic imaging, experimental (athero)thrombosis studies, histology, in silico drug design, proteomics, specific platelet function tests and a vessel-on-a-chip approach using microfluidics. The PhD candidate will work together with different research groups within the Netherlands and abroad (Germany, UK, USA).

The candidate has a Master’s degree in biomedical sciences, medical biology, biochemistry or comparable.

The candidate is highly motivated, holds a solution-oriented mindset, and is a true team player.

The candidate should have good verbal and written English communication skills (at least C1 level according to the Common European Framework of Reference).

Fixed-term contract: 4 years.

Temporary employment for 4 years. Your salary would be € 2.325,- gross per month in the first year up to € 2.972,- gross per month in the fourth year according to the PhD-candidate salary scale. Each year an evaluation will take place.

The terms of employment of Maastricht University are set out in the Collective Labour Agreement of Dutch Universities (CAO). Furthermore, local UM provisions also apply. For more information look at the website www.maastrichtuniversity.nl > Support > UM employees.

Maastricht University is renowned for its unique, innovative, problem-based learning system, which is characterized by a small-scale and student-oriented approach. Research at UM is characterized by a multidisciplinary and thematic approach, and is concentrated in research institutes and schools. Maastricht University has around 16,300 students and 4,300 employees. Reflecting the university's strong international profile, a fair amount of both students and staff are from abroad. The university hosts 6 faculties: Faculty of Health, Medicine and Life Sciences, Faculty of Law, School of Business and Economics, Faculty of Science and Engineering, Faculty of Arts and Social Sciences, Faculty of Psychology and Neuroscience.

http://www.maastrichtuniversity.nl/

CARIM

The Cardiovascular Research Institute Maastricht (CARIM), School for Cardiovascular Diseases, is one of the top institutes for translational cardiovascular research in Europe. It is among the world leaders in the fields of research into vascular and thrombotic disorders and atrial fibrillation as well as translational heart failure research. It has also made important international contributions to molecular imaging in the cardiovascular field.

With an annual budget of approximately 20 mln Euros in 2018, CARIM is one of the largest cardiovascular research institutes in Europe, producing more than 500 scientific articles and approximately 40 PhD dissertations per year. CARIM employs 250 researchers from 13 disciplines, about 100 PhD students and 40 technical and support staff members.

Over the last ten years, CARIM papers have been published in high-impact journals such as the New England Journal of Medicine, JAMA, Nature Medicine, Nature Cell Biology, Cell Metabolism, Journal of Experimental Medicine, Circulation, Lancet Neurology, and the Journal of the American College of Cardiology. Bibliometric analyses illustrate that CARIM publications have been cited 1.97 times more often than the world average for the cardiovascular field in the period of 2009 until 2012.

CARIM is recognized by the KNAW as a research school and as an international training site for Early Stage Researchers in the framework of the Marie Curie Program.

Cardiovascular scientists from around the world join CARIM because it values open communication, close cooperation, high ambitions, good facilities and a critical learning environment.

https://www.carimmaastricht.nl/?culture=en-GB