Postdoctoral Researcher – 3D nanoscopy to study physical principles of DNA repair

Postdoctoral Researcher – 3D nanoscopy to study physical principles of DNA repair

Published Deadline Location
23 Sep 31 Dec Delft

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Experienced with advanced fluorescence microscopy and keen to uncover mechanisms of DNA repair? Come join our interdisciplinary team!

Job description

A 2-year Postdoctoral Researcher position is available in a collaborative project between the Gruβmayer Lab ( in the Department of Bio Nanoscience (TU Delft) and the Kanaar lab ( in the Department of Molecular Genetics (Erasmus MC). The project can start from October 2022 and the vacancy will remain open until a suitable candidate is found.


The Gruβmayer lab develops advanced 3D light microscopy methods (SMLM/SOFI/SIM, quantitative phase imaging) to perform quantitative studies in live cells to answer fundamental questions in molecular and cell biology. The Kanaar lab works on the understanding of the fundamental mechanisms of DNA repair from molecules in cells to patients.


In this project we will study the mechanisms by which DNA repair proteins organize themselves during the repair of DNA damage by novel single-molecule and super-resolution microscopy techniques in living cells. The postdoctoral researcher will perform live-cell microscopy experiments and contribute to image analysis. This project will be part of a network of postdocs working on projects that converge research done at TU Delft with Erasmus MC.


Delft University of Technology (TU Delft)


We are looking for a creative, motivated and result-driven candidate that has recently completed a PhD in (bio)physics, molecular biology or related quantitative discipline, and has experimental experience in fluorescence imaging and analysis.

  • Experience in handling living biological samples is preferred.
  • Programming skills in Python or similar language is highly desirable.
  • The candidate should have a high degree of independence and should be capable of good time- and project-management.
  • Affinity for teaching and guiding students.
  • Demonstrated proficiency in expressing yourself verbally and in writing in English and proven affinity for scientific writing.
  • The ability to work in a team and take initiative.

 All candidates will receive consideration regardless of gender, race, religion, sexual orientation, disability status, and all other characteristics protected by law. We encourage all qualified candidates to apply, and we especially welcome applications from historically underrepresented minorities in the STEM field.

Conditions of employment

Fixed-term contract: 2 years.

The position is for 2 years.

The TU Delft offers a customisable compensation package, a discount for health insurance and sport memberships, and a monthly work costs contribution. Flexible work schedules can be arranged. An International Children’s Centre offers child care and an international primary school. Dual Career Services offers support to accompanying partners. Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities.


Delft University of Technology

Delft University of Technology is built on strong foundations. As creators of world-famous Dutch waterworks and pioneers in biotech, TU Delft is a top international university combining science, engineering and design. It delivers world class results in education, research and innovation to address challenges in the areas of energy, climate, mobility, health and digital society. For generations, our engineers have proven to be entrepreneurial problem-solvers, both in business and in a social context. At TU Delft we embrace diversity and aim to be as inclusive as possible (see our Code of Conduct). Together, we imagine, invent and create solutions using technology to have a positive impact on a global scale.
Challenge. Change. Impact! 



Faculty Applied Science

With more than 1,000 employees, including 135 pioneering principal investigators, as well as a population of about 3,400 passionate students, the Faculty of Applied Sciences is an inspiring scientific ecosystem. Focusing on key enabling technologies, such as quantum- and nanotechnology, photonics, biotechnology, synthetic biology and materials for energy storage and conversion, our faculty aims to provide solutions to important problems of the 21st century. To that end, we train students in broad Bachelor's and specialist Master's programmes with a strong research component. Our scientists conduct ground-breaking fundamental and applied research in the fields of Life and Health Science & Technology, Nanoscience, Chemical Engineering, Radiation Science & Technology, and Engineering Physics. We are also training the next generation of high school teachers and science communicators.


Department Bionanoscience
The Department of Bionanoscience focuses on the fundamental understanding of biological processes, from the level of single molecules to the full complexity of living cells. This research provides fascinating insight in the molecular mechanisms that lead to cellular function. Furthermore it enables the in vitro bottom-up construction of cellular machinery and it impacts applications ranging from biomolecular diagnostics to novel antibiotics and targeted nanomedicine. The department features a strongly multidisciplinary and international team of scientists, whose research areas include single-molecule biophysics, synthetic biology, as well as (quantitative) cell biology.


  • Postdoc
  • Natural sciences
  • 36—38 hours per week
  • €2960—€4670 per month
  • Doctorate
  • TUD02790


Delft University of Technology (TU Delft)

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